Sunday, July 10, 2011

Colon and Rectum Cancer

It is estimated that 142,570 men and women (72,090 men and 70,480 women) will be diagnosed with and 51,370 men and women will die of cancer of the colon and rectum in 20101.


The following information is based on NCI’s SEER Cancer Statistics Review2.Use the links on this page to learn more about each statistic type:
  1. Incidence & Mortality
  2. Survival & Stage
  3. Lifetime Risk
  4. Prevalence
Incidence & Mortality


SEER Incidence
 From 2004-2008, the median age at diagnosis for cancer of the colon and rectum was 70 years of age3. Approximately 0.1% were diagnosed under age 20; 1.1% between 20 and 34; 3.9% between 35 and 44; 12.8% between 45 and 54; 19.6% between 55 and 64; 24.1% between 65 and 74; 26.2% between 75 and 84; and 12.2% 85+ years of age.


The age-adjusted incidence rate was 47.2 per 100,000 men and women per year. These rates are based on cases diagnosed in 2004-2008 from 17 SEER geographic areas.


US Mortality


From 2003-2007, the median age at death for cancer of the colon and rectum was 75 years of age4. Approximately 0.0% died under age 20; 0.6% between 20 and 34; 2.4% between 35 and 44; 8.1% between 45 and 54; 15.6% between 55 and 64; 22.2% between 65 and 74; 30.4% between 75 and 84; and 20.6% 85+ years of age.


The age-adjusted death rate was 17.6 per 100,000 men and women per year. These rates are based on patients who died in 2003-2007 in the US.


Trends in Rates


Trends in rates can be described in many ways. Information for trends over a fixed period of time, for example 1996-2008, can be evaluated by the annual percentage change (APC) (See Fast Stats for trends over fixed time intervals) . If there is a negative sign before the number, the trend is a decrease; otherwise it is an increase. If there is an asterisk after the APC then the trend was significant, that is, one believes that it is beyond chance, i.e. 95% sure, that the increase or decrease is real over the period 1996-2008. If the trend is not significant, the trend is usually reported as stable or level. Joinpoint analyses can be used over a long period of time to evaluate when changes in the trend have occurred along with the APC which shows how much the trend has changed between each of the joinpoints.




Survival & Stage


Survival can be calculated by different methods for different purposes. The survival statistics presented here are based on relative survival, which measures the survival of the cancer patients in comparison to the general population to estimate the effect of cancer. The overall 5-year relative survival for 2001-2007 from 17 SEER geographic areas was 64.3%. Five-year relative survival by race and sex was: 65.5% for white men; 64.5% for white women; 55.0% for black men; 56.9% for black women.
The stage distribution is based on Summary Stage 2000. (See Fast Stats for more detailed statistics)


Lifetime Risk


Based on rates from 2005-2007, 5.12% of men and women born today will be diagnosed with cancer of the colon and rectum at some time during their lifetime. This number can also be expressed as 1 in 20 men and women will be diagnosed with cancer of the colon and rectum during their lifetime. These statistics are called the lifetime risk of developing cancer. Sometimes it is more useful to look at the probability of developing cancer of the colon and rectum between two age groups. For example, 2.04% of men will develop cancer of the colon and rectum between their 50th and 70th birthdays compared to 1.53% for women. (See Fast Stats for more detailed statistics, and Probability of Developing and Dying of Cancer for methodology)


Prevalence


On January 1, 2008, in the United States there were approximately 1,110,077 men and women alive who had a history of cancer of the colon and rectum -- 542,127 men and 567,950 women. This includes any person alive on January 1, 2008 who had been diagnosed with cancer of the colon and rectum at any point prior to January 1, 2008 and includes persons with active disease and those who are cured of their disease. Prevalence can also be expressed as a percentage and it can also be calculated for a specific amount of time prior to January 1, 2008 such as diagnosed within 5 years of January 1, 2008. (See Fast Stats for more detailed statistics, and Overview of Prevalence Statistics for methodology)

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